In a scholarly study published in todays online problem of Neurobiology of Aging

Alzheimer’s and diabetes link Diabetic people have a significantly higher risk of growing Alzheimer’s disease but the molecular connection between the two remains unexplained. Today, researchers at the Salk Institute for Biological Studies determined the probable molecular basis for the diabetes – Alzheimer’s interaction . In a scholarly study published in today’s online problem of Neurobiology of Aging, investigators led by David R. Schubert, Ph.D., professor in the Cellular Neurobiology Laboratory, record that the arteries in the mind of young diabetic mice are broken by the conversation of elevated blood sugar levels characteristic of diabetes and low degrees of beta amyloid, a peptide that clumps to create the senile plaques that riddle the brains of Alzheimer’s individuals.

Alzheimer’s disease patients present improvement in trial of new drug A new drug has been shown to improve the brain function of people with early stage Alzheimer’s disease and reduce an integral protein associated with the disease in the spinal fluid, in a little study published today in the journal Lancet Neurology and presented at the 2008 Alzheimer’s Association International Conference on Alzheimer’s Disease. The drug, known as PBT2, counteracts the creation and build-up of a proteins called amyloid-beta occurring in Alzheimer’s disease. This protein, which can build up into a ‘plaque’, is normally thought to be toxic to mind cells also to prevent them from functioning properly. Seventy-eight individuals with early stage Alzheimer’s disease took either 50mg or 250mg dosages of the medication PBT2, or a placebo, during the period of 12 weeks in a randomised, double-blind clinical trial, led by a researcher from Imperial College London working with co-workers in Australia and Sweden.

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